FIGURE

Fig 9

ID

ZDB-FIG-200206-9

Publication

Hin et al., 2020 - Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2

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Fig 9

Summary of the molecular changes in the brains of zebrafish due to aging and/or the K115fs-like mutation (<italic>psen1</italic><sup>K97fs/+</sup>).

For each of the four pairwise comparisons shown, the summarised molecular changes (↑ = overall increased, ↓ = overall decreased, • = significant alterations but not in an overall direction) were inferred from a combination of the following analyses: functional enrichment analysis of differentially expressed genes and proteins, promoter motif enrichment analysis of differentially expressed genes, gene set enrichment analysis of differentially expressed genes, and weighted co-expression network analysis of the gene expression data.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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