Lab
A. Kawakami Lab
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Statement of Research Interest
All genome sequence data have been determined in many organisms including human being. However, we still don't know how these genes act to make up our body, morphology, organs and even our behaviors and individual differences.
During development, any kind of biological phenomenon, for example the organizer in early development, midline signaling from notochord/floor plate and somite segmentation, includes the transmission of information between cells through signaling molecules. In addition, many other molecules also play important roles inside and outside of the cells to relay the information to the gene regulation. To understand "the black box" between genes and phenomena, we think it is important to know the signaling cascade and regulation.
We aim to explore the pathway between "signal" and "phenomena" through the developmental genetic approach using zebrafish.
During development, any kind of biological phenomenon, for example the organizer in early development, midline signaling from notochord/floor plate and somite segmentation, includes the transmission of information between cells through signaling molecules. In addition, many other molecules also play important roles inside and outside of the cells to relay the information to the gene regulation. To understand "the black box" between genes and phenomena, we think it is important to know the signaling cascade and regulation.
We aim to explore the pathway between "signal" and "phenomena" through the developmental genetic approach using zebrafish.
Lab Members