Phenotype: histone H4K20me methyltransferase activity disrupted, abnormal
Note: This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.
Name: histone H4K20me methyltransferase activity
Synonyms: histone H4 methyl lysine(20) N-methyltransferase activity (H4-K20 specific), histone H4-K20 dimethylation, histone H4K20 dimethylation, histone H4K20me methylase activity
Definition: Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2.
Ontology: GO: Molecular Function [GO:0140941]    QuickGO    AmiGO
Name: disrupted
Synonyms:
Definition: A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course.
Ontology: Phenotypic Quality Ontology [PATO:0001507]