| Phenotype: | lysosome-rich enterocyte vacuole decreased area, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | lysosome-rich enterocyte |
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| Synonyms: | |
| Definition: | Enterocytes that possess a large supranuclear vacuolar system that preferentially internalize dietary protein via receptor-mediated and fluid-phase endocytosis for intracellular digestion and trans-cellular transport. In zebrafish these cells are located in the posterior region of the mid intestine throughout life. In mammals they are found in the ileum pre-weaning and later are replaced by mature enterocytes . |
| Ontology: | Anatomy Ontology [ZFA:0005942] |
| Name: | vacuole |
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| Synonyms: | vacuolar carboxypeptidase Y |
| Definition: | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
| Ontology: | GO: Cellular Component [GO:0005773] QuickGO AmiGO |
| Name: | decreased area |
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| Synonyms: | |
| Definition: | An area which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002058] |