Phenotype: | hindbrain ganglioside GM1 increased amount, abnormal |
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Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
Name: | hindbrain |
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Synonyms: | rhombencephalon |
Definition: | The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata and thus these are not distinguished here. From Neuroanatomy of the Zebrafish Brain. |
Ontology: | Anatomy Ontology [ZFA:0000029] |
Name: | ganglioside GM1 |
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Synonyms: | (2S,3R,4E)-3-hydroxy-2-(octadecanoylamino)octadec-4-en-1-yl 5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-[beta-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1->4)]-beta-D-galactopyranosyl-(1->4)-be, (Neu5Ac)GM1, alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-octadecanoylsphingosine, alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-stearoylsphingosine, alpha-Neup5Ac-(2->3)-[beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-N-stearoylsphingosine, G(M1) Ganglioside, Galbeta1->3GalNAcbeta1->4(Neu5Acalpha2->3)Galbeta1->4Glcbeta1->1-Cer, Galbeta1->3GalNAcbeta1->4(NeuAcalpha2->3)Galbeta1->4Glc-Cer, Ganglioside A2, Ganglioside G4, Ganglioside GGtet1, Ganglioside GI, Ganglioside GM1, Ganglioside GM1 (18:1/18:0), Ganglioside GM1a, Ganglioside M1, GM1, GM1 ganglioside, monosialoganglioside GM1, Monosialosyl tetraglycosyl ceramide, Sialosylganglio-N-tetraosylceramide |
Definition: | A sialotetraosylceramide consisting of a branched pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage. |
Ontology: | ChEBI [CHEBI:61048] ( EBI ) |
Name: | increased amount |
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Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
Definition: | An amount which is relatively high. |
Ontology: | Phenotypic Quality Ontology [PATO:0000470] |