Phenotype: midbrain ganglioside GM1 increased amount, abnormal
Note: This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.
Name: midbrain
Synonyms: mesencephalon
Definition: The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally.
Ontology: Anatomy Ontology [ZFA:0000128]
Name: ganglioside GM1
Synonyms: (2S,3R,4E)-3-hydroxy-2-(octadecanoylamino)octadec-4-en-1-yl 5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-[beta-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1->4)]-beta-D-galactopyranosyl-(1->4)-be, (Neu5Ac)GM1, alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-octadecanoylsphingosine, alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-stearoylsphingosine, alpha-Neup5Ac-(2->3)-[beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-N-stearoylsphingosine, G(M1) Ganglioside, Galbeta1->3GalNAcbeta1->4(Neu5Acalpha2->3)Galbeta1->4Glcbeta1->1-Cer, Galbeta1->3GalNAcbeta1->4(NeuAcalpha2->3)Galbeta1->4Glc-Cer, Ganglioside A2, Ganglioside G4, Ganglioside GGtet1, Ganglioside GI, Ganglioside GM1, Ganglioside GM1 (18:1/18:0), Ganglioside GM1a, Ganglioside M1, GM1, GM1 ganglioside, monosialoganglioside GM1, Monosialosyl tetraglycosyl ceramide, Sialosylganglio-N-tetraosylceramide
Definition: A sialotetraosylceramide consisting of a branched pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.
Ontology: ChEBI [CHEBI:61048]  ( EBI )
Name: increased amount
Synonyms: accessory, increased, increased number, present in greater numbers in organism, supernumerary
Definition: An amount which is relatively high.
Ontology: Phenotypic Quality Ontology [PATO:0000470]
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