| Phenotype: | synaptic transmission, cholinergic amplitude, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | synaptic transmission, cholinergic |
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| Synonyms: | cholinergic synaptic transmission |
| Definition: | The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. |
| Ontology: | GO: Biological Process [GO:0007271] QuickGO AmiGO |
| Name: | amplitude |
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| Synonyms: | |
| Definition: | A physical quality of a process inhering in a bearer by virtue of the size of the bearer's maximum displacement from the 'normal' position, when periodic motion is taking place. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000080] |