| Phenotype: | pronephric glomerulus lacks parts or has fewer parts of type glomerular basement membrane glomerular endothelium fenestra, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | pronephric glomerulus |
|---|---|
| Synonyms: | pronephric glomera, pronephric glomeruli, pronephric glomus |
| Definition: | Paired highly vascularized structures of the pronephros which are fused at the midline. Responsible for blood filtration and begins to function between 40 and 48hpf. |
| Ontology: | Anatomy Ontology [ZFA:0001557] |
| Name: | lacks parts or has fewer parts of type |
|---|---|
| Synonyms: | loss of |
| Definition: | The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001999] |
| Name: | glomerular basement membrane |
|---|---|
| Synonyms: | glomerular filtration membrane |
| Definition: | Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space. |
| Ontology: | Anatomy Ontology [ZFA:0005285] |
| Name: | glomerular endothelium fenestra |
|---|---|
| Synonyms: | GEnC fenestration, glomerular endothelial cell fenestration |
| Definition: | A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. |
| Ontology: | GO: Cellular Component [GO:0036053] QuickGO AmiGO |