| Phenotype: | intestinal epithelium adherens junction incomplete structure, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | intestinal epithelium |
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| Synonyms: | intestine epithelium, villous epithelium |
| Definition: | Simple columnar epithelium that lines the intestine, sometimes pseudostratified, with absorptive brush-border cells and mucous goblet cells clearly visible. |
| Ontology: | Anatomy Ontology [ZFA:0005124] |
| Name: | adherens junction |
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| Synonyms: | cell-cell adherens junction |
| Definition: | A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. |
| Ontology: | GO: Cellular Component [GO:0005912] QuickGO AmiGO |
| Name: | incomplete structure |
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| Synonyms: | |
| Definition: | A structural quality inhering in a bearer by virtue of the bearer's lacking parts or having a reduced form compared to fully formed entities. |
| Ontology: | Phenotypic Quality Ontology [PATO:0005013] |