| Phenotype: | retinal ganglion cell cysteine-type endopeptidase activity decreased occurrence, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | retinal ganglion cell |
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| Synonyms: | gangliocyte, RGC |
| Definition: | The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. |
| Ontology: | Anatomy Ontology [ZFA:0009310] |
| Name: | cysteine-type endopeptidase activity |
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| Synonyms: | lysosomal cysteine-type endopeptidase, metacaspase activity, thiol endopeptidase activity |
| Definition: | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
| Ontology: | GO: Molecular Function [GO:0004197] QuickGO AmiGO |
| Name: | decreased occurrence |
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| Synonyms: | decreased incidence |
| Definition: | An occurrence which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002052] |