ZFIN Phenotype Statement: double-strand break repair via homologous recombination decreased frequency, abnormal

Phenotype:	double-strand break repair via homologous recombination decreased frequency, abnormal
Note:	This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.

Name:	double-strand break repair via homologous recombination
Synonyms:	HDR, homologous recombinational repair, homology-directed repair, HRR, Rad51-dependent recombinational repair, Rhp51-dependent recombinational repair
Definition:	The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Ontology:	GO: Biological Process [GO:0000724] QuickGO AmiGO

Name:	decreased frequency
Synonyms:	infrequent, low frequency
Definition:	A frequency which is relatively low.
Ontology:	Phenotypic Quality Ontology [PATO:0000381]