| Phenotype: | osteoblast rough endoplasmic reticulum decreased amount, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | osteoblast |
|---|---|
| Synonyms: | osteoblasts |
| Definition: | A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. |
| Ontology: | Anatomy Ontology [ZFA:0009031] |
| Name: | rough endoplasmic reticulum |
|---|---|
| Synonyms: | RER, rough ER |
| Definition: | The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. |
| Ontology: | GO: Cellular Component [GO:0005791] QuickGO AmiGO |
| Name: | decreased amount |
|---|---|
| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |