Search Ontology:
GO: Biological Process

ubiquitin-dependent protein catabolic process via the N-end rule pathway

Term ID
GO:0071596
Synonyms
  • ubiquitin-dependent protein breakdown via the N-end rule pathway
  • ubiquitin-dependent protein catabolism via the N-end rule pathway
  • ubiquitin-dependent protein degradation via the N-end rule pathway
Definition
The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes