Search Ontology:
GO: Biological Process

nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay

Term ID
GO:0070479
Synonyms
  • 5'-3' NMD
  • 5'-3' nonsense-mediated decay
  • 5'-3' nonsense-mediated mRNA decay
  • nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay
  • nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay
  • nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay
Definition
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. 18554525
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes