Search Ontology:
GO: Biological Process

cornification

Term ID
GO:0070268
Synonyms
Definition
A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). 18846107
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is part of
is a type of
has_part
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes