Search Ontology:
GO: Biological Process

Wnt signaling pathway, planar cell polarity pathway

Term ID
GO:0060071
Synonyms
  • PCP pathway
  • planar cell polarity pathway
  • Wnt receptor signaling pathway, planar cell polarity pathway
  • Wnt receptor signalling pathway, planar cell polarity pathway
  • Wnt-activated signaling pathway, planar cell polarity pathway
  • Wnt-JNK signaling pathway
  • Wnt-PCP signaling pathway
Definition
A type of non-canonical Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the activation small G proteins such as Rho, Rac, and Cdc42 which, in turn activate effectors, including C-Jun N-terminal kinase (JNK) and Rho kinase (Rok). The signaling ends with change in the transcription of target genes and/or reorganisation of the cytoskeleton. (4)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes