Search Ontology:
GO: Molecular Function

methotrexate binding

Term ID
GO:0051870
Synonyms
Definition
Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes