Search Ontology:
GO: Molecular Function

branched-chain alpha-keto acid dehydrogenase activity

Term ID
GO:0047101
Synonyms
  • 2-oxoisovalerate dehydrogenase (acylating) activity
  • 2-oxoisovalerate dehydrogenase activity
  • 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)
Definition
Catalysis of the reaction: [a branched-chain alpha-keto acid] + CoA + NAD+ = [a branched-chain acyl-CoA] + CO2 + NADH. This enzyme system catalyzes the oxidative decarboxylation of branched-chain alpha-keto acids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs. 1.2.1.25
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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