tyrosine 3-monooxygenase activity

Term ID

GO:0004511

Synonyms

L-tyrosine hydroxylase activity
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)
tyrosine 3-hydroxylase activity
tyrosine hydroxylase activity

Definition

Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O. 1.14.16.2

References

EC:1.14.16.2
MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN
RHEA:18201
Reactome:R-HSA-209823

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen Show first 5 Terms
positively regulated by: positive regulation of tyrosine 3-monooxygenase activity

positive regulation of tyrosine 3-monooxygenase activity Show first 5 Terms
regulated by: regulation of tyrosine 3-monooxygenase activity

regulation of tyrosine 3-monooxygenase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes