squalene monooxygenase activity

Term ID

GO:0004506

Synonyms

• squalene 2,3-oxidocyclase activity
• squalene epoxidase activity
• squalene hydroxylase activity
• squalene oxydocyclase activity
• squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity
• squalene-2,3-epoxidase activity
• squalene-2,3-epoxide cyclase activity

Definition

Catalysis of the reaction: H+ + NADPH + O2 + squalene = (S)-2,3-epoxysqualene + H2O + NADP+.

References

• EC:1.14.14.17
• KEGG_REACTION:R02874
• MetaCyc:SQUALENE-MONOOXYGENASE-RXN
• RHEA:25282
• Reactome:R-HSA-191299

Ontology

GO: Molecular Function    QuickGO    AmiGO