Search Ontology:
GO: Molecular Function

methylenetetrahydrofolate reductase (NAD(P)H) activity

Term ID
GO:0004489
Synonyms
  • 5,10-CH(2)-H(4)folate reductase activity
  • 5,10-CH2-H4folate reductase activity
  • 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity
  • 5,10-methylenetetrahydrofolate reductase (FADH) activity
  • 5,10-methylenetetrahydrofolate reductase (FADH2) activity
  • 5,10-methylenetetrahydrofolate reductase (NADPH) activity
  • 5,10-methylenetetrahydrofolate reductase activity
  • 5,10-methylenetetrahydrofolic acid reductase activity
  • 5,10-methylenetetrahydropteroylglutamate reductase activity
  • 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity
  • 5-methyltetrahydrofolate:NAD oxidoreductase activity
  • 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity
  • 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity
  • 5-methyltetrahydrofolate:NAD+ oxidoreductase activity
  • 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity
  • 5-methyltetrahydrofolate:NADP+ oxidoreductase activity
  • MetF
  • methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity
  • methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity
  • methylenetetrahydrofolate reductase (NADPH(2)) activity
  • methylenetetrahydrofolate reductase (NADPH2)
  • methylenetetrahydrofolate reductase [NAD(P)H]
  • methylenetetrahydrofolate reductase activity
  • methylenetetrahydrofolic acid reductase activity
  • MTHFR activity
  • N(5),N(10)-methylenetetrahydrofolate reductase activity
  • N(5,10)-methylenetetrahydrofolate reductase activity
  • N5,10-methylenetetrahydrofolate reductase activity
  • N5,N10-methylenetetrahydrofolate reductase activity
Definition
Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+. (2)
References
  • EC:1.5.1.20
  • KEGG_REACTION:R01224
  • KEGG_REACTION:R07168
  • MetaCyc:1.5.1.20-RXN
  • Reactome:R-HSA-200676
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
regulated by
Phenotype
Phenotype caused by Genes