Search Ontology:
GO: Molecular Function

leukotriene-C4 synthase activity

Term ID
GO:0004464
Synonyms
  • (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)
  • (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)
  • leukotriene A(4):glutathione S-leukotrienyltransferase activity
  • leukotriene A4:glutathione S-leukotrienyltransferase activity
  • leukotriene C(4) synthetase activity
  • leukotriene C4 synthetase activity
  • leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)
  • LTC(4) synthase activity
  • LTC(4) synthetase activity
  • LTC4 synthase activity
  • LTC4 synthetase activity
Definition
Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). 4.4.1.20
References
  • EC:4.4.1.20
  • KEGG_REACTION:R03059
  • MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN
  • RHEA:17617
  • Reactome:R-HSA-266050
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes