arachidonate 12(S)-lipoxygenase activity

Term ID

GO:0004052

Synonyms

• 12-lipoxygenase activity
• 12Delta-lipoxygenase activity
• 12S-lipoxygenase activity
• arachidonate:oxygen 12-oxidoreductase activity
• C-12 lipoxygenase activity
• delta12-lipoxygenase activity
• leukotriene A4 synthase
• LTA4 synthase activity

Definition

Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate. 1.13.11.31

References

• EC:1.13.11.31
• KEGG_REACTION:R01596
• MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN
• RHEA:10428
• Reactome:R-HSA-2161948
• Reactome:R-HSA-2161950
• Reactome:R-HSA-2161964
• Reactome:R-HSA-9024983
• Reactome:R-HSA-9025957
• Reactome:R-HSA-9026006
• Reactome:R-HSA-9026007

Ontology

GO: Molecular Function    QuickGO    AmiGO