Search Ontology:
GO: Molecular Function

DNA-(apurinic or apyrimidinic site) endonuclease activity

Term ID
GO:0003906
Synonyms
  • AP endonuclease class I activity
  • AP site-DNA 5'-phosphomonoester-lyase activity
  • apurinic/apyrimidinic endodeoxyribonuclease activity
  • deoxyribonuclease (apurinic or apyrimidinic) activity
  • DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity
  • endonuclease VIII activity
  • UV endonuclease
Definition
Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). AP_endonuclease
References
  • Reactome:R-HSA-110375
  • Reactome:R-HSA-5649711
  • Reactome:R-HSA-5649725
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes