Search Ontology:
GO: Molecular Function

transcription coregulator activity

Term ID
GO:0003712
Synonyms
  • nuclear receptor coreceptor activity
  • RNA polymerase II transcriptional cofactor activity
  • transcription cofactor activity
  • transcription coreceptor activity
  • transcriptional co-regulator
Definition
A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. (5)
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes