Search Ontology:
GO: Cellular Component

exosome (RNase complex)

Term ID
GO:0000178
Synonyms
  • exosome (ribonucleasease complex)
  • exosome multienzyme ribonuclease complex
Definition
A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. (3)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
has subtype
Phenotype
Phenotype caused by Genes