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Human Disease

graft-versus-host disease

Term ID
DOID:0081267
Synonyms
  • graft versus host disease
  • GvHD
Definition
An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32. (2)
References
Ontology
Human Disease   ( DOID:0081267 )
Relationships
is a type of
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Genes Involved
Zebrafish Models