Search Ontology:
ChEBI

Ro 25-6981

Term ID
CHEBI:92897
Synonyms
  • (alphaR,betaS)-alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidinepropanol
  • 4-[(1R,2S)-1-hydroxy-2-methyl-3-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol
  • 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol
  • Ro 25-6981 free base
  • Ro-25-6981
  • Ro25-6981
Definition
A member of the class of piperidines that is 4-benzylpiperidine substituted by a 3-hydroxy-3-(4-hydroxyphenyl)-2-methylpropyl group at position 1 (the 1R,2S-stereoisomer). It is a potent antagonist of the GluN2B subunit of the N-methyl-D-aspartate (NMDA) receptor.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from Ro 25-6981
Phenotype where environments contain Ro 25-6981
Phenotype modified by environments containing Ro 25-6981
Human Disease / Model Data