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ChEBI

(2R,3S)-EHNA hydrochloride

Term ID
CHEBI:64139
Synonyms
  • (2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol hydrochloride
  • (2R,3S)-3-(adenin-9-yl)-2-nonanol hydrochloride
  • (2R,3S)-9-(2-hydroxy-3-nonyl)adenine hydrochloride
  • (2R,3S)-EHNA.HCl
  • (R,S)-6-amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol hydrochloride
  • erythro-9-(2-hydroxy-3-nonyl)adenine hydrochloride
Definition
A hydrochloride salt obtained by reaction of (2R,3S)-EHNA with one equivalent of hydrochloric acid. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase.
References
  • Reaxys:4729841
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from (2R,3S)-EHNA hydrochloride
Phenotype where environments contain (2R,3S)-EHNA hydrochloride
Phenotype modified by environments containing (2R,3S)-EHNA hydrochloride
Human Disease / Model Data