Search Ontology:
ChEBI
volasertib
- Term ID
- CHEBI:231358
- Synonyms
-
- BI 6727
- BI-6727
- BI6727
- N-{(1r,4R)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-6-oxo-8-(propan-2-yl)-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide
- volasertib
- volasertibum
- Definition
- A member of the class of pteridines that is (7R)-7-ethyl-5-methyl-8-(propan-2-yl)-7,8-dihydropteridin-6(5H)-one substituted by a [4-({trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}carbamoyl)-2-methoxyphenyl]amino group at position 2. It is as polo-like kinase 1 inhibitor (IC50 = 0.87 nM) with potential antineoplastic activity.
- References
-
- CAS:755038-65-4
- DrugBank:DB12062
- HMDB:HMDB0259868
- KEGG:D10182
- PDBeChem:IBI
- PMID:19383823
- PMID:22119200
- PMID:23956067
- PMID:24339028
- PMID:24755882
- PMID:24884503
- PMID:25089571
- PMID:26412161
- PMID:27793694
- PMID:28881742
- PMID:29228610
- PMID:29476067
- PMID:30118839
- PMID:31741706
- PMID:32468878
- PMID:32509401
- PMID:32951163
- PMID:33139055
- PMID:33561562
- PMID:34001596
- PMID:34143546
- PMID:34350385
- PMID:34710325
- PMID:35597904
- PMID:35644070
- PMID:36199185
- PMID:36382510
- PMID:36505864
- PMID:36845678
- PMID:37454493
- PMID:37765111
- PMID:38165424
- PMID:38540116
- Wikipedia:Volasertib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 9 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from volasertib
Phenotype where environments contain volasertib
Phenotype modified by environments containing volasertib
Human Disease / Model Data