Search Ontology:
ChEBI

orteronel

Term ID
CHEBI:231353
Synonyms
  • (+)-orteronel
  • (S)-orteronel
  • 6-[(7S)-7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide
  • orteronel
  • orteronelum
  • TAK 700
  • TAK-700
  • TAK700
Definition
A member of the class of pyrroloimidazoles that is 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole substituted by hydroxy and 6-(methylcarbamoyl)naphthalen-2-yl groups at position 7 (the 7S-stereoisomer). It is a non-steroidal 17,20-lyase inhibitor that suppresses androgen synthesis. It was previously in clinical development for the treatment of castration-resistant prostate cancer -- trial now discontinued.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from orteronel
Phenotype where environments contain orteronel
Phenotype modified by environments containing orteronel
Human Disease / Model Data
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