Search Ontology:
ChEBI
AZD7762
- Term ID
- CHEBI:131156
- Synonyms
-
- (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
- 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-3-piperidinyl]-2-thiophenecarboxamide
- 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide
- 3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide
- 5-(3-fluorophenyl)-3-ureidothiophene-2-carboxylic acid N-[(S)-piperidin-3-yl]amide
- 5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
- AZD 7762
- AZD-7762
- Definition
- A member of the class of thiophenes that is thiophene substituted by N-[(3S)-piperidin-3-yl]aminocarbonyl, carbamoylamino, and 3-fluorophenyl groups at positions 2, 3 and 5, respectively. It is a potent ATP-competitive checkpoint kinase inhibitor (IC50 = 5 nM for Chk1).
- References
-
- CAS:860352-01-8
- DrugBank:DB12242
- LINCS:LSM-42751
- PDBeChem:YDJ
- PMID:18790776
- PMID:20233881
- PMID:22189968
- PMID:22551018
- PMID:22653969
- PMID:22825736
- PMID:23892959
- PMID:24362713
- PMID:24448638
- PMID:26853940
- PMID:27272773
- PMID:27829217
- PMID:28049532
- PMID:28088043
- PMID:28754670
- PMID:29777684
- PMID:30015873
- PMID:30633885
- PMID:30763067
- PMID:31372095
- PMID:32857208
- PMID:32878802
- PMID:33114206
- PMID:34314706
- PMID:35972603
- PMID:36398929
- PMID:37006282
- PMID:37449977
- PMID:38948053
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 6 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from AZD7762
Phenotype where environments contain AZD7762
Phenotype modified by environments containing AZD7762
Human Disease / Model Data