Term Name: | lumacaftor |
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Synonyms: | 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid, lumacaftor, VRT 826809, VRT-826809, VX 809, VX-809 |
Definition: | An aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis. |
Ontology: | ChEBI [CHEBI:90951] ( EBI ) |