ZFIN ID: ZDB-EXP-170915-7
Experiment Conditions Description: chemical treatment by environment: Cyclopamine, chemical treatment by environment: calciol
chemical treatment by environment: Cyclopamine
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: Cyclopamine
Synonyms: Cyclopamine
Definition:
Ontology: ChEBI [CHEBI:4021]  ( EBI )
chemical treatment by environment: calciol
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: calciol
Synonyms: (+)-vitamin D3, (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol, activated 7-dehydrocholesterol, calciol, CC, Cholecalciferol, colecalciferol, Delta-D, oleovitamin D3, vitamin D3
Definition: A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.
Ontology: ChEBI [CHEBI:28940]  ( EBI )
Publication: Cortes et al., 2015