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Fig. 1
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Figure Caption
mab21l2 mutants possess complex eye defects that include small lenses, microphthalmia, coloboma, and corneal malformations. A‐L,N,O: Whole‐mount images of wild‐type (A‐E,K,L) and mab21l2 −/− (F‐J,N,O) mutant embryos. Compared with wild‐type embryos, mab21l2 −/− mutants display lens defects, microphthalmia and misshapen eyes beginning at 24 hpf (compare A‐E,K,L with F‐J,N,O). Arrowheads in I, J indicate colobomas present in mab21l2 −/− mutants. M,P,Q‐U: Ventral whole‐mount images of wild‐type (G,J) and mab21l2 −/− (H,I,K) embryos at time points indicated. Note corneal malformations and lens displacement in mab21l2 −/− mutants (arrows in P,R,S,U). Scale bars = 100 μm
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