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Figure 3

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ZDB-IMAGE-190723-1820
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Figures for Klüver et al., 2011
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Figure 3 APM mediated <italic>hspb11</italic> induction depends on nAChR activity and increased intracellular calcium levels.

(A) hspb11 expression analysis in ache and sopfixe−/− zebrafish mutant embryos at 48 hpf. (B) hspb11 expression in sopfixe null mutants and siblings (+/?  =  heterozygous and wildtype) after APM (6 µM) exposure (26–50 hpf). (C) 1 µM Thapsigargin (TG) and 2 mM caffeine (CAF) induce hspb11 expression in zebrafish embryos (exposure period 48–50 hpf). Bars represent the relative gene expression as fold change of the respective untreated control as mean ± standard deviation of three independent replicate exposures Control  =  ctrl. * P<0.05.

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