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Fig. 3
S1pr2 is required for the subduction and active migration of myocardial precursors. (A-L) Overlays of GFP-labeled endoderm (as revealed by immunofluorescence) and nxk2.5 expression (as revealed by whole-mount in situ hybridization), in embryos at the stages indicated. (A′-L′) Transverse sections of the embryos shown in A-L. Red dashed lines indicate lateral boundaries of the endodermal sheet; yellow lines denote width of the area covered by the myocardial populations; arrowheads indicate myocardial cells; arrows indicate that myocardial cells are located above (yellow) and below (red) the endoderm. Scale bars: 100 µm.