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Fig. 5
PMELa MO reduces the number of cylindrical melanosomes to a greater extent than PMELb MO. (A–D) Electron micrographs highlighting melanosome morphology at 2dpf for zebrafish injected with control (A), PMELa (B), PMELb (C) and PMELa&b MOs (D). Scale bars: 1µm. (E) The PMELa&b MO resulted in a decrease in the number of melanosomes. Ctrl, control. (F) All PMEL MOs resulted in a significant loss of cylindrical melanosomes. PMELa had a greater effect on melanosome shape than the PMELb MO. Results show the mean±s.e.m. *P<0.05, **P<0.01, ***P<0.001 (Student′s t-test).
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Full text @ J. Cell Sci.