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Fig. 3

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ZDB-IMAGE-130318-13
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Figures for Lu et al., 2013
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Fig. 3 Rhythmic expression of aanat2 is initiated in pinealocytes of embryos with open neural tubes. Dorsal views of embryos raised in 14:10 h light:dark cycle fixed at indicated time points. (A) GFP mRNA injected control embryos with oval pineal glands. (B) lft1 mRNA injected embryos with divided pineal glands. Closed arrowheads indicate pineals with high aanat2 expression; open arrowheads indicate pineals with low aanat2 expression. ZT indicates time within the circadian cycle, lights turning on at ZT=0 and lights turning off at ZT=14. Dark bars indicate lights off and light bars indicate lights on. For each time point, ne10 for embryos with oval shaped pineal and embryos with divided pineal. Scale bar=25 μm.

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Reprinted from Developmental Biology, 374(2), Lu, P.N., Lund, C., Khuansuwan, S., Schumann, A., Harney-Tolo, M., Gamse, J.T., and Liang, J.O., Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus, 333-344, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.