Gene
kcnab2b
- ID
- ZDB-GENE-080219-36
- Name
- potassium voltage-gated channel subfamily A regulatory beta subunit 2b
- Symbol
- kcnab2b Nomenclature History
- Previous Names
-
- zgc:171453
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have aldo-keto reductase (NADP) activity; ion channel binding activity; and potassium channel regulator activity. Involved in regulation of action potential and regulation of transmission of nerve impulse. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane; juxtaparanode region of axon; and voltage-gated potassium channel complex. Is expressed in Mauthner neurons. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Watanabe et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Watanabe et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR023210 | NADP-dependent oxidoreductase domain |
Family | IPR005399 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
Family | IPR005400 | Potassium channel, voltage-dependent, beta subunit, KCNAB1 |
Family | IPR005401 | Potassium channel, voltage-dependent, beta subunit, KCNAB2 |
Family | IPR005983 | Potassium channel, voltage-dependent, beta subunit, KCNAB |
Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
Protein | Length | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily | Potassium channel, voltage-dependent, beta subunit, KCNAB | Potassium channel, voltage-dependent, beta subunit, KCNAB1 | Potassium channel, voltage-dependent, beta subunit, KCNAB2 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PF37
|
346 | ||||||
UniProtKB:E9QGU5
|
412 | ||||||
UniProtKB:A0A8M2B927
|
454 | ||||||
UniProtKB:A0A8M2B9B9
|
397 | ||||||
UniProtKB:A0A8M9PT49
|
379 | ||||||
UniProtKB:A0A8M9PWJ3
|
455 | ||||||
UniProtKB:A0A8M2B970
|
469 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
aberrant processed transcript |
kcnab2b-201
(1)
|
Havana | 1787 nt | |
mRNA |
kcnab2b-202
(1)
|
Havana | 1239 nt |
Interactions and Pathways
No data available
Plasmids
No data available