Gene
slc6a8
- ID
- ZDB-GENE-071024-2
- Name
- solute carrier family 6 member 8
- Symbol
- slc6a8 Nomenclature History
- Previous Names
-
- ct1 (1)
- chot1
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have symporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to localize to plasma membrane. Is expressed in several structures, including digestive system; eye; heart; optic vesicle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in creatine transporter deficiency and intellectual disability. Orthologous to human SLC6A8 (solute carrier family 6 member 8).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
cerebral creatine deficiency syndrome 1 | Alliance | Cerebral creatine deficiency syndrome 1 | 300352 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Sodium:neurotransmitter symporter | Sodium:neurotransmitter symporter superfamily |
---|---|---|---|
UniProtKB:A0A8M1P953
|
652 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
slc6a8-201
(1)
|
Havana | 2126 nt |
Interactions and Pathways
No data available
Plasmids
No data available