Gene

cd247

ID
ZDB-GENE-061130-4
Name
CD247 molecule
Symbol
cd247 Nomenclature History
Previous Names
  • cd3zeta
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in intestine; lymphocyte; ovary; and spleen. Orthologous to human CD247 (CD247 molecule).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cd247 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 25 Alliance ?Immunodeficiency 25 610163
Associated With cd247 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR021663 T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit
Family IPR024128 T-cell surface glycoprotein CD3 zeta subunit
Repeat IPR003110 Phosphorylated immunoreceptor signalling ITAM
Domain Details Per Protein
Protein Length Phosphorylated immunoreceptor signalling ITAM T-cell surface glycoprotein CD3 zeta subunit T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit
UniProtKB:A7KX13 153
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations