Gene
gamt
- ID
- ZDB-GENE-051030-97
- Name
- guanidinoacetate N-methyltransferase
- Symbol
- gamt Nomenclature History
- Previous Names
-
- zgc:123136
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have guanidinoacetate N-methyltransferase activity. Predicted to be involved in creatine biosynthetic process. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and yolk. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Orthologous to human GAMT (guanidinoacetate N-methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
guanidinoacetate methyltransferase deficiency | Alliance | Cerebral creatine deficiency syndrome 2 | 612736 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Arginine N-methyltransferase 2-like domain | Guanidinoacetate N-methyltransferase | RMT2/GAMT Methyltransferase | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
---|---|---|---|---|---|
UniProtKB:Q71N41
|
234 | ||||
UniProtKB:A8E5I0
|
234 |
Interactions and Pathways
No data available
Plasmids
No data available