Gene
trpa1b
- ID
- ZDB-GENE-050106-1
- Name
- transient receptor potential cation channel, subfamily A, member 1b
- Symbol
- trpa1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Exhibits calcium-release channel activity. Involved in chemosensory behavior; detection of chemical stimulus involved in sensory perception of pain; and ion transmembrane transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Is expressed in Rohon-Beard neurons and cranial ganglion. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Faucherre et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial episodic pain syndrome 1 | Alliance | ?Episodic pain syndrome, familial, 1 | 615040 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Ion transport domain | Transient receptor potential cation channel |
|---|---|---|---|---|---|
|
UniProtKB:B6D5I5
|
1107 | ||||
|
UniProtKB:Q5UM14
|
1120 | ||||
|
UniProtKB:A0A8M9PU11
|
985 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
trpa1b-201
(1)
|
Havana | 4100 nt | |
| mRNA |
trpa1b-202
(1)
|
Havana | 3324 nt | |
| mRNA |
trpa1b-203
(1)
|
Ensembl | 5993 nt |
Interactions and Pathways
No data available
Plasmids