Gene

tlr8a

ID
ZDB-GENE-040219-13
Name
toll-like receptor 8a
Symbol
tlr8a Nomenclature History
Previous Names
  • TIR8.2 (1)
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to have DNA binding activity; RNA binding activity; and transmembrane signaling receptor activity. Predicted to be involved in several processes, including defense response to other organism; regulation of cytokine secretion; and toll-like receptor signaling pathway. Predicted to localize to integral component of membrane. Is expressed in blood; heart; liver; and pleuroperitoneal region. Orthologous to human TLR8 (toll like receptor 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tlr8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Immunodeficiency 98 with autoinflammation, X-linked 301078
Associated With tlr8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Repeat IPR026906 BspA-type LRR region
Domain Details Per Protein
Protein Length BspA-type LRR region Cysteine-rich flanking region, C-terminal Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype Toll/interleukin-1 receptor homology (TIR) domain Toll/interleukin-1 receptor homology (TIR) domain superfamily
UniProtKB:A0A8M1QHF1 1019
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations