Gene

map4k2

ID
ZDB-GENE-030616-163
Name
mitogen-activated protein kinase kinase kinase kinase 2
Symbol
map4k2 Nomenclature History
Previous Names
  • map4k2l
  • si:dz150l22.2
  • si:dz263j20.1
  • zgc:136670
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have MAP kinase kinase kinase kinase activity. Predicted to be involved in activation of protein kinase activity; intracellular signal transduction; and regulation of mitotic cell cycle. Predicted to localize to cytoplasm. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Nguyen et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map4k2 Human Ortholog
No data available
Associated With map4k2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001180 Citron homology (CNH) domain
Family IPR021160 Mitogen-activated protein (MAP) kinase kinase kinase kinase
Family IPR050629 STE20/SPS1-related Proline-Alanine-rich Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Citron homology (CNH) domain Mitogen-activated protein (MAP) kinase kinase kinase kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily STE20/SPS1-related Proline-Alanine-rich Kinase
UniProtKB:Q1RLZ2 865
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations