Gene
orc6
- ID
- ZDB-GENE-030131-2976
- Name
- origin recognition complex, subunit 6
- Symbol
- orc6 Nomenclature History
- Previous Names
-
- orc6l
- wu:fa94a09
- wu:fc22h10
- zgc:65798
- zgc:77185
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to localize to nuclear origin of replication recognition complex. Is expressed in central nervous system; eye; intermediate cell mass of mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Orthologous to human ORC6 (origin recognition complex subunit 6).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65798 (1 image)
- IMAGE:6907825 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Maerz et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Meier-Gorlin syndrome 3 | Alliance | Meier-Gorlin syndrome 3 | 613803 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | ORC6, first cyclin-like domain | Origin recognition complex, subunit 6, metazoa/plant |
---|---|---|---|
UniProtKB:Q6ZM36
|
256 |
Interactions and Pathways
No data available
Plasmids
No data available