Gene

tlcd3ba

ID

ZDB-GENE-030131-2046

Name

TLC domain containing 3Ba

Symbol

tlcd3ba Nomenclature History

Previous Names

fam57ba
fb95d07
wu:fb95d07
zgc:73225

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have sphingosine N-acyltransferase activity. Involved in several processes, including central nervous system development; eye development; and lipid homeostasis. Predicted to localize to endoplasmic reticulum. Is expressed in brain; central nervous system; epiphysis; head; and neurons. Orthologous to human TLCD3B (TLC domain containing 3B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73225 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tlcd3ba Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
cone-rod dystrophy 22	Alliance	Cone-rod dystrophy 22	619531

Associated With tlcd3ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006634	TRAM/LAG1/CLN8 homology domain
Family	IPR050846	TLC domain-containing

Domain Details Per Protein

Protein	Length	TLC domain-containing	TRAM/LAG1/CLN8 homology domain
UniProtKB:X1WH51 InterPro	193
UniProtKB:A0A8M2BB48 InterPro	161
UniProtKB:Q6PBV7 InterPro	242
UniProtKB:A0A8M2BBE5 InterPro	292

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fam57ba-202 (1) Ensembl	Havana	745 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam57ba-203 (1) Ensembl	Havana	923 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam57ba-204 (1) Ensembl	Havana	886 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam57ba-205 (1) Ensembl	Havana	911 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam57ba-206 (1) Ensembl	Havana	891 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam57ba-208 (1) Ensembl	Havana	1382 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	tlcd3ba-201 (1) Ensembl	Ensembl	1141 nt	Select Tool ZFIN BLAST
ncRNA	fam57ba-007 (1) Ensembl	Havana	680 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations