CRISPR

CRISPR2-cog4

ID
ZDB-CRISPR-190913-2
Name
CRISPR2-cog4
Previous Names
None
Target
Sequence
5' - GCTCTGCAGGACCTGCAGCG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
b1312 cog4
Expression
Gene expression in Wild Types + CRISPR2-cog4
No data available
Phenotype
Phenotype resulting from CRISPR2-cog4
No data available
Phenotype of all Fish created by or utilizing CRISPR2-cog4
Phenotype Fish Conditions Figures
pillar of the lateral semicircular canal absent, abnormal cog4b1312/b1312 standard conditions Fig. S5 with image from Clément et al., 2018
anterior macula Golgi apparatus structure, abnormal cog4b1312/b1312 standard conditions Fig. S11 from Ferreira et al., 2018
protein N-linked glycosylation process quality, abnormal cog4b1312/b1312 standard conditions Fig. S12 from Ferreira et al., 2018
semicircular canal Collagen present, abnormal cog4b1312/b1312 standard conditions Fig. S5 with image from Clément et al., 2018
extracellular matrix organization disrupted, abnormal cog4b1312/b1312 standard conditions Fig. 5 with imageFig. 6 with imageFig. S4 with image from Clément et al., 2018
otic vesicle protrusion proteoglycan decreased amount, abnormal cog4b1312/b1312 standard conditions Fig. 5 with imageFig. S4 with image from Clément et al., 2018
protein O-linked glycosylation process quality, abnormal cog4b1312/b1312 standard conditions Fig. S12 from Ferreira et al., 2018
otic vesicle ventral protrusion present, abnormal cog4b1312/b1312 standard conditions Fig. S5 with image from Clément et al., 2018
semicircular canal formation delayed, abnormal cog4b1312/b1312 standard conditions Fig. 3 with imageFig. S5 with image from Clément et al., 2018
inner ear malformed, abnormal cog4b1312/b1312 standard conditions Fig. 6 from Ferreira et al., 2018
otic vesicle protrusion Collagen decreased amount, abnormal cog4b1312/b1312 standard conditions Fig. 6 with image from Clément et al., 2018
hair cell anterior macula stereocilium bundle decreased amount, abnormal cog4b1312/b1312 standard conditions Fig. 6 from Ferreira et al., 2018
auditory behavior decreased occurrence, abnormal cog4b1312/b1312 standard conditions text only from Ferreira et al., 2018
inner ear morphology, abnormal cog4b1312/b1312 standard conditions Fig. S3 with image from Clément et al., 2018
inner ear decreased size, abnormal cog4b1312/b1312 standard conditions Fig. 1 with image from Clément et al., 2018
pillar of the semicircular canal malformed, abnormal cog4b1312/b1312 standard conditions Fig. 1 with imageFig. 3 with imageFig. S5 with image from Clément et al., 2018
otic vesicle lacks parts or has fewer parts of type otic vesicle protrusion, abnormal cog4b1312/b1312 standard conditions Fig. 3 with image from Clément et al., 2018
neuromast hair cell stereocilium bundle decreased amount, abnormal cog4b1312/b1312 standard conditions Fig. 6 from Ferreira et al., 2018
semicircular canal aplastic/hypoplastic, abnormal cog4b1312/b1312 standard conditions Fig. 1 with image from Clément et al., 2018
whole organism glycosphingolipid decreased amount, abnormal cog4b1312/b1312 standard conditions Fig. S12 from Ferreira et al., 2018
semicircular canal shape, abnormal cog4b1312/b1312 standard conditions Fig. 6 from Ferreira et al., 2018
inner ear lacks parts or has fewer parts of type semicircular canal, abnormal cog4b1312/b1312 standard conditions Fig. 3 with image from Clément et al., 2018
ceratohyal cartilage chondrocyte disorganized, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
eye decreased size, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
mandibular arch skeleton decreased size, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
inner ear decreased size, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
pectoral fin decreased length, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
whole organism decreased length, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
ceratohyal cartilage chondrocyte morphology, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
pectoral fin col1a2 expression decreased amount, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
pectoral fin clavate, abnormal cog4b1311/+; cog4b1312/+ standard conditions Fig. 7 from Ferreira et al., 2018
hair cell anterior macula cog4 expression decreased amount, abnormal cog4b1312/b1312; vu234Tg standard conditions Fig. S14 from Ferreira et al., 2018
Citations