CRISPR

CRISPR2-wwtr1

ID
ZDB-CRISPR-181210-4
Name
CRISPR2-wwtr1
Previous Names
None
Target
Sequence
5' - GGAGTCTCCCGGGGCT - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM sequence was "CGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
swu46 wwtr1
swu47 wwtr1
Expression
Gene expression in Wild Types + CRISPR2-wwtr1
No data available
Phenotype
Phenotype resulting from CRISPR2-wwtr1
No data available
Phenotype of all Fish created by or utilizing CRISPR2-wwtr1
Phenotype Fish Conditions Figures
whole organism wwtr1 expression decreased amount, abnormal wwtr1swu46/swu46 standard conditions Fig. 2 from Yi et al., 2018
swim bladder decreased size, abnormal wwtr1swu46/swu46 (AB/TU) standard conditions Fig. 1 with image from Yi et al., 2019
chorion micropyle formation decreased occurrence, abnormal wwtr1swu46/swu46 (AB/TU) standard conditions Fig. 5 with image from Yi et al., 2019
micropylar cell wwtr1 expression absent, abnormal wwtr1swu46/swu46 (AB/TU) standard conditions Fig. 5 with image from Yi et al., 2019
whole organism wwtr1 expression absent, abnormal wwtr1swu46/swu46 (AB/TU) standard conditions Fig. 1 with image from Yi et al., 2019
pericardium edematous, abnormal wwtr1swu46/swu46 (AB/TU) standard conditions Fig. 1 with image from Yi et al., 2019
fertilized egg chrorion micropyle absent, abnormal wwtr1swu46/+ (AB/TU) standard conditions Fig. 4 with image from Yi et al., 2019
embryo development arrested, abnormal wwtr1swu46/+ (AB/TU) standard conditions Fig. 2 with image from Yi et al., 2019
fertilization decreased occurrence, abnormal wwtr1swu46/+ (AB/TU) standard conditions Fig. 4 with image from Yi et al., 2019
fertilized egg pronucleus decreased amount, abnormal wwtr1swu46/+ (AB/TU) standard conditions Fig. 4 with image from Yi et al., 2019
chorion micropyle formation decreased occurrence, abnormal wwtr1swu46/+ (AB/TU) standard conditions Fig. 4 with image from Yi et al., 2019
embryo development arrested, abnormal wwtr1swu47/+ (AB/TU) standard conditions Fig. 2 with image from Yi et al., 2019
intestine decreased size, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
intestine fabp2 expression decreased distribution, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
intestinal rod endodermal cell distributed, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver decreased size, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver fabp1a expression decreased amount, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver fabp1a expression spatial pattern, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
intestine morphology, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
exocrine pancreas prss1 expression decreased distribution, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver mislocalised, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
lateral plate mesoderm mislocalised, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 4 from Yi et al., 2018
liver split bilaterally, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
intestine fabp2 expression decreased amount, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver prox1a expression decreased amount, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
exocrine pancreas prss1 expression spatial pattern, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
exocrine pancreas split bilaterally, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver prox1a expression increased distribution, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver prox1a expression spatial pattern, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
exocrine pancreas prss1 expression decreased amount, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
exocrine pancreas decreased size, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 3 from Yi et al., 2018
liver cell population proliferation decreased occurrence, abnormal wwtr1swu46/+; yap1swu45/swu45 standard conditions Fig. 4 from Yi et al., 2018
trunk morphology, abnormal wwtr1swu46/swu46; yap1swu45/swu45 standard conditions Fig. 2 from Yi et al., 2018
caudal fin curved dorsal, abnormal wwtr1swu46/swu46; yap1swu45/swu45 standard conditions Fig. 2 from Yi et al., 2018
developmental process delayed, abnormal wwtr1swu46/swu46; yap1swu45/swu45 standard conditions Fig. 2 from Yi et al., 2018
trunk decreased length, abnormal wwtr1swu46/swu46; yap1swu45/swu45 standard conditions Fig. 2 from Yi et al., 2018
whole organism morphology, abnormal wwtr1swu46/swu46; yap1swu45/swu45 standard conditions Fig. 2 from Yi et al., 2018
whole organism decreased length, abnormal wwtr1swu46/swu46; yap1swu45/swu45 standard conditions Fig. 2 from Yi et al., 2018
Citations